📘 CodingMarble Learn

Biochemistry: The Chemistry of Life

Plants build glucose by photosynthesis: 6 CO2 + 6 H2O + light gives C6H12O6 + 6 O2. Four families of big molecules (carbohydrates, proteins, fats, nucleic acids) are built from small units. Cells break nutrients down to release energy, with enzymes speeding every step. Proteins are made by reading DNA, copying it to mRNA and joining amino acids on a ribosome.

🎬 Step-by-step story

  1. Plants make food from air and water. 6 carbon dioxide and 6 water, with light, make 1 glucose and 6 oxygen. Count the balls on both sides.
  2. Big molecules are chains of small units. Sugar units make carbohydrates. Amino acids make proteins. Fat is glycerol with 3 tails. Nucleotides make DNA.
  3. Our cells break glucose down with oxygen. We get carbon dioxide, water and energy. It is photosynthesis run backwards.
  4. An enzyme is a tiny helper protein. It fits one chain like a key in a lock and cuts it into small units. That is digestion.
  5. To make a protein, DNA is copied to a short mRNA. The ribosome reads it and joins amino acids in order.
  6. Your turn. Choose a family and slide the number of units. Watch the chain grow.

Tip: drag the 3D scene to turn it. Use two fingers to zoom.

🤔 Common doubts, cleared

Where does the oxygen of photosynthesis come from?

It comes from the water molecules. Count the 6 oxygen molecules made on the product side.

Why are proteins so different if they use the same 20 amino acids?

The order and length of the chain differ, like words made from the same letters.

Is respiration the opposite of photosynthesis?

Its equation is the reverse. Cells use glucose and oxygen and give back CO2, water and energy.

Does the enzyme get used up?

No. It fits, cuts, lets go and works again on the next chain.

How does a cell know the order of amino acids?

The DNA gene order is copied into mRNA. The ribosome reads three letters at a time and picks one amino acid for each.

Photosynthesis: how plants make glucose

Green plants take carbon dioxide from the air and water from the soil. Using light energy caught by chlorophyll, they build glucose and release oxygen:

6 CO2 + 6 H2O + light → C6H12O6 + 6 O2

Count the atoms: 6 C, 12 H and 18 O on each side, so the equation is balanced. Light energy is stored in the bonds of glucose. This is the start of almost every food chain.

Structure of biomolecules

Living things use four main families of large molecules. Most are polymers: long chains made of many small repeating units.

Units join by a reaction that removes a water molecule (condensation). Breaking them needs water added back (hydrolysis).

Breakdown of nutrients

Digestion cuts big molecules into small ones so the body can absorb them: starch to glucose, proteins to amino acids, fats to glycerol and fatty acids.

Inside cells, glucose is burned slowly with oxygen to release energy for work (respiration):

C6H12O6 + 6 O2 → 6 CO2 + 6 H2O + energy

This is the reverse of photosynthesis. Enzymes are proteins that speed up each step. Each enzyme fits one kind of molecule, like a key in a lock, and is not used up.

Protein synthesis in steps

The order of nucleotides in a gene in DNA holds the recipe for a protein. Cells make it in steps:

  1. Transcription: a short copy of the gene, mRNA, is made in the nucleus.
  2. The mRNA moves to a ribosome in the cytoplasm.
  3. Translation: the ribosome reads the mRNA three letters at a time. Each triplet picks one amino acid.
  4. Amino acids are joined in that order into a chain, which then folds into the working protein.

A change in the DNA order can change the amino acids and so the protein.

Key formulas and definitions

Worked examples

1. How many oxygen molecules are made when 3 glucose molecules are made by photosynthesis?

One glucose comes with 6 O2. So 3 glucose come with 3 × 6 = 18 oxygen molecules.

2. A chain of 10 amino acids is made. How many water molecules are removed when the units join?

Each join removes 1 water. 10 units need 9 joins, so 9 water molecules are removed.

3. Which enzyme-type job happens when bread tastes sweet after chewing?

Salivary amylase cuts starch into small sugars (maltose and glucose). The small sugars taste sweet.

4. A piece of mRNA has 12 letters. How many amino acids does it code for?

The ribosome reads 3 letters per amino acid. 12 ÷ 3 = 4 amino acids.

Common mistakes

Practice quiz

1. Photosynthesis produces:
2. Proteins are chains of:
3. An enzyme is a:
4. Where does translation happen?
5. Breaking glucose with oxygen gives:

Practice: answer these yourself

Type or choose your answer, then press Check. Use a hint if you are stuck; the full solution appears after you answer.

Frequently asked questions

What is biochemistry?

Biochemistry is the study of the chemical substances and reactions in living things, such as photosynthesis, digestion and protein making.

What are the four main biomolecules?

Carbohydrates, proteins, fats (lipids) and nucleic acids (DNA and RNA).

What is the equation of photosynthesis?

6 CO2 + 6 H2O + light energy → C6H12O6 + 6 O2.

Where this is taught

NetherlandsHAVO 5 (eindexamenjaar)Society and chemical technology
NetherlandsVWO 6 (eindexamenjaar)Society, chemistry and technology
Japan高校(専門学科)1〜3年Advanced Biology

Learn first

Learn next

Related lessons

All Chemistry lessons