Poland Liceum ogólnokształcące, klasa I Biology
Chapters: 4
1. I. Chemistry of life
Inorganic components · Organic components
- Biomolecules – A cell is mostly water, plus four big families of carbon compounds: proteins, carbohydrates, lipids and nucleic acids. Grinding tissue in acid separates small molecules (acid-soluble pool) from big ones – proteins, polysaccharides and nucleic acids (acid-insoluble pool). Proteins are chains of amino acids folded into four levels of structure. Polysaccharides are chains of sugars; lipids are fatty acids on glycerol; nucleic acids are chains of nucleotides. Enzymes are protein catalysts that bind a substrate at the active site, lower the activation energy, and are affected by temperature, pH, substrate level and inhibitors.
2. II. The cell
Eukaryotic cell and membrane
- The Cell: Basic Unit of Life – Every living thing is made of cells. Robert Hooke first saw cells in cork in 1665. Cells are prokaryotic (no true nucleus, like bacteria) or eukaryotic (true nucleus). Plant cells have a cell wall, chloroplasts and a big vacuole; animal cells do not. Each organelle has a job. Water enters and leaves cells by osmosis. Cells make new cells by mitosis (growth) and meiosis (sex cells).
3. III. Energy and metabolism
Metabolism and ATP · Enzymes · Cellular respiration
- Metabolism: How Cells Build, Break and Use Energy – Metabolism is the full set of chemical reactions inside a living thing. Breaking big molecules into small ones is catabolism; it gives out energy. Building big molecules from small ones is anabolism; it uses energy. ATP carries the energy between the two, like a rechargeable battery. Each reaction is sped up by its own enzyme, and the reactions link into chains called metabolic pathways.
- Enzymes – Enzymes are proteins that act as biological catalysts: they speed up reactions in cells without being used up. Each enzyme has an active site that fits only one kind of substrate (specificity). Enzymes work by lowering the activation energy. They work best at an optimum temperature and pH; too much heat or the wrong pH changes the active site's shape and denatures them.
- Respiration: Aerobic, Anaerobic and the Human Lungs – Respiration is the breakdown of food, usually glucose, inside cells to release energy, stored as ATP. With oxygen (aerobic) glucose is fully broken into carbon dioxide and water and gives much energy; without oxygen (anaerobic) it gives little energy and makes ethanol (yeast) or lactic acid (muscles). Our lungs bring oxygen to the blood through millions of alveoli.
4. IV. Cell division
Cell cycle, mitosis and meiosis
- Cell Cycle and Cell Division – A cell grows, copies its DNA and splits in a fixed order called the cell cycle: interphase (G1, S, G2) and M phase. In S phase the DNA doubles (2C → 4C) but the chromosome number stays the same. Mitosis (prophase, metaphase, anaphase, telophase) and cytokinesis give two cells identical to the parent – it is an equational division used for growth and repair. Meiosis has two divisions; in meiosis I homologous chromosomes pair, cross over and separate, halving the chromosome number (2n → n). It makes four haploid cells for gametes and creates variation.