Japan 高校1年 Basic Biology
Chapters: 3
1. Characteristics of living things
Features of living things · Genes and their function
- The Cell: Basic Unit of Life – Every living thing is made of cells. Robert Hooke first saw cells in cork in 1665. Cells are prokaryotic (no true nucleus, like bacteria) or eukaryotic (true nucleus). Plant cells have a cell wall, chloroplasts and a big vacuole; animal cells do not. Each organelle has a job. Water enters and leaves cells by osmosis. Cells make new cells by mitosis (growth) and meiosis (sex cells).
- Molecular Basis of Inheritance – DNA is the genetic material in most living things (some viruses use RNA). It is a double helix: two antiparallel strands of nucleotides, A pairs with T by 2 hydrogen bonds and G with C by 3. Long DNA is packed on histones into nucleosomes and then chromatin. DNA copies itself semi-conservatively (Meselson–Stahl). The central dogma says DNA → RNA → protein. Transcription makes RNA from one strand; in eukaryotes the hnRNA is capped, tailed and spliced. The genetic code is a triplet, has 64 codons (61 for amino acids, 3 stops), starts with AUG, is nearly universal and degenerate. Ribosomes translate mRNA into protein with tRNA adaptors. Genes are switched on and off; the lac operon is the classic example. The Human and Rice Genome Projects read whole genomes, and DNA fingerprinting uses repeat DNA (VNTRs) to identify people.
2. Regulation of the human body
Nervous and endocrine regulation · Immunity
- Nervous System, Reflex Action and the Human Brain – Nerve cells (neurons) carry messages as electric impulses and pass them to the next cell with chemicals across a gap called a synapse. Quick safety responses (reflexes) are handled by the spinal cord; thinking and control come from the brain, which is guarded by the skull and a fluid cushion.
- The Immune System: How Your Body Fights Germs – Germs (pathogens) cause infectious disease. The body has three lines of defence: barriers (skin, mucus, acid), a fast general (innate) response (inflammation, fever, phagocytes) and a slow, specific (adaptive) response (B cells make antibodies, T cells kill infected cells). Memory cells make the second attack fast. Vaccines create memory safely. Immunity can go wrong: allergy, autoimmune disease, immunodeficiency (e.g. HIV).
3. Biodiversity and ecosystems
Vegetation and succession · Ecosystems and conservation
- Ecosystem, Food Chains and Energy Flow – An ecosystem is all the living things in a place plus the non-living things around them, working together. Energy enters as sunlight, passes one way up a food chain, and only about 10% moves to each next level.